SCHEMBL5446010

SCHEMBL5446010

O[C@@H](CCc1ccccc1)CCC1[CH]CCC1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 1/20 0.43
PTGFR P43088 1/20 0.43
PTGER2 P43116 1/20 0.43
LTB4R Q15722 2/20 0.41
LTB4R2 Q9NPC1 2/20 0.41
SLCO2A1 Q92959 1/20 0.39
SLC18A2 Q05940 1/20 0.39
DPP4 P27487 1/20 0.38
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37
MMP14 P50281 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570849 0.81 SLC18A2 (0.47) SLC18A2
SCHEMBL4256995 0.78 LTB4R (0.53) PTGER1PTGFRPTGER2LTB4RLTB4R2
SCHEMBL31354792 0.77 LTB4R (0.52) PTGER1PTGFRPTGER2LTB4RLTB4R2
SCHEMBL6567840 0.76 SLC18A2 (0.46) SLC18A2
SCHEMBL4799370 0.75 MMP2 (0.55) DPP4MMP2MMP9MMP12MMP13
SCHEMBL2557825 0.74 PTGER1 (0.42) PTGER1PTGFRPTGER2LTB4RLTB4R2
SCHEMBL22350151 0.73 PTGER1 (0.49) PTGER1PTGFRPTGER2LTB4RLTB4R2
SCHEMBL22350147 0.73 PTGER1 (0.49) PTGER1PTGFRPTGER2LTB4RLTB4R2
SCHEMBL4256993 0.73 MMP12 (0.47) PTGER1PTGFRPTGER2DPP4MMP2
SCHEMBL27516839 0.72 PTGER1 (0.48) PTGER1PTGFRPTGER2LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070092467-A1 Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers L'OREAL (FR) 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070092467-A1 Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers HPGD, KRT18, PTGS1 PTGER1 43/4885PTGFR 36/4885PTGER2 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.