Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065339 | 1.00 | AGXT (0.42) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL4604877 | 0.85 | KMT2A (0.45) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL5984224 | 0.78 | RAB9A (0.41) | HTTMAPTSMN1; SMN2FGFR1NPC1 | |
| SCHEMBL9708898 | 0.76 | WDR5 (0.42) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL9812452 | 0.76 | KMT2A (0.41) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL5197626 | 0.76 | KMT2A (0.41) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL4958916 | 0.76 | KMT2A (0.41) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL13136704 | 0.75 | PKM (0.42) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL13203871 | 0.75 | KMT2A (0.41) | AGXTKMT2AWDR5PDE10AATP4A | |
| SCHEMBL13011306 | 0.75 | KMT2A (0.41) | AGXTKMT2AWDR5PDE10AATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615624-A2 | ORAL PHARMACEUTICAL PREPARATION COMPRISING A PROTON PUMP ANTAGONIST AND A BASIC EXCIPIENT | ALTANA Pharma AG (DE) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089342-A2 | ORAL PHARMACEUTICAL PREPARATION COMPRISING A PROTON PUMP ANTAGONIST AND A BASIC EXIPIENT | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |
| EP-1326609-A2 | STABLE ORAL FORMULATION CONTAINING BENZIMIDAZOLE DERIVATIVE | Galephar M/F (BE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032425-A2 | STABLE ORAL FORMULATION CONTAINING BENZIMIDAZOLE DERIVATIVE | GALEPHAR M/F (BE) | 2002-04-25 | — | — | WO | disclosed |
| EP-0991407-A2 | STABILIZATION OF ACID SENSITIVE BENZIMIDAZOLS WITH AMINO/CYCLODEXTRIN COMBINATIONS | HEXAL AG (DE) | 2000-04-12 | — | — | EP | disclosed |
| US-5929244-A | TREATING AN ENANTIOMERICALLY ENRICHED PREPARATION OF THE COMPOUND IN FAVOUR OF ITS (+) OR (-)-ENANTIOMER AT ROOM TEMPERATURE OR BELOW WITH A SOLVENT SELECTED FROM KETONES, ESTERS, ALCOHOL, NITRILES, HYROCARBONS, ETHERS, AMIDES | ASTRA AKTIEBOLAG (SE) | 1999-07-27 | — | — | US | disclosed |
| US-5877192-A | Enantiomer provides improved antisecretory effect and a better clinical effect | ASTRA AKTIEBOLAG (SE) | 1999-03-02 | — | — | US | disclosed |
| US-5817338-A | PLASTICIZING COMPOUND TO MINIZE REDUCTION OF ACID RESISTANCE | ASTRA AKTIEBOLAG (SE) | 1998-10-06 | — | — | US | disclosed |
| WO-1998040069-A2 | STABILIZATION OF ACID SENSITIVE BENZIMIDAZOLES WITH AMINO ACID/CYCLODEXTRIN COMBINATIONS | HEXAL AG (DE) | 1998-09-17 | — | — | WO | disclosed |
| US-5753265-A | ADENOSINE TRIPHOSPHATASE INHIBITOR; INHIBITS GASTIC ACID SECRETION IN MAMMALS | ASTRA AKTIEBOLAG (SE) | 1998-05-19 | — | — | US | disclosed |
| US-5714504-A | ALKALINE SALTS OF OMEPRAZOLE; ANTIULCER AGENTS; MAGNESIUM OMEPRAZOLE OR SODIUM OMEPRAZOLE FOR EXAMPLE | ASTRA AKTIEBOLAG (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5714504-A | ALKALINE SALTS OF OMEPRAZOLE; ANTIULCER AGENTS; MAGNESIUM OMEPRAZOLE OR SODIUM OMEPRAZOLE FOR EXAMPLE | ASTRA AKTIEBOLAG (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5693818-A | SEPARATING DIASTEROMERIC ESTERS, DISSOLVING EACH IN ALKALINE SOLTION TO HYDROLYZE ESTER GROUP, NEUTRALIZING OPTICALLY PURE INTACT ENANTIOMERS | ASTRA AKTIEBOLAG (SE) | 1997-12-02 | — | — | US | disclosed |
| US-5693818-A | SEPARATING DIASTEROMERIC ESTERS, DISSOLVING EACH IN ALKALINE SOLTION TO HYDROLYZE ESTER GROUP, NEUTRALIZING OPTICALLY PURE INTACT ENANTIOMERS | ASTRA AKTIEBOLAG (SE) | 1997-12-02 | — | — | US | disclosed |