Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.34 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440142 | 0.83 | PKM (0.33) | RAB9ANPC1MAPTSMN1; SMN2IDO1 | |
| SCHEMBL5448791 | 0.80 | MAPT (0.40) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL5943999 | 0.78 | MAPT (0.45) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL5988718 | 0.78 | AGXT (0.42) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL30065339 | 0.78 | AGXT (0.42) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL9264444 | 0.77 | TGFBR1 (0.37) | NPC1MAPTSMN1; SMN2HTTCSF1R | |
| SCHEMBL3665713 | 0.77 | MAPT (0.52) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL13138466 | 0.76 | RAB9A (0.46) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL28087593 | 0.75 | RAB9A (0.42) | RAB9ANPC1MAPTSMN1; SMN2IDO1 | |
| SCHEMBL24572635 | 0.73 | RAB9A (0.38) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615624-A2 | ORAL PHARMACEUTICAL PREPARATION COMPRISING A PROTON PUMP ANTAGONIST AND A BASIC EXCIPIENT | ALTANA Pharma AG (DE) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089342-A2 | ORAL PHARMACEUTICAL PREPARATION COMPRISING A PROTON PUMP ANTAGONIST AND A BASIC EXIPIENT | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |
| US-5948789-A | ASYMMETRIC OXIDATION OF A PRO-CHIRAL SULPHIDE TO THE SINGLE ENANTIOMERS OR AN ENANTIOMERICALLY ENRICHED FORM OF THE CORRESPONDING SULPHOXIDE. OPTICALLY PURE SUBSTITUTED 2-(2-PYRIDINYLMETHYL-SULPHINYL)-1H-BENZIMIDAZOLES. | ASTRA AKTIEBOLAG (SE) | 1999-09-07 | — | — | US | disclosed |