SCHEMBL5451212

SCHEMBL5451212

COC(=O)C(C(=O)OC)=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.48
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
TSHR P16473 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALOX15 P16050 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPT P10636 2/20 0.44
LMNA P02545 2/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
PTGS2 P35354 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5325112 0.80 CA1 (0.59) HPGDCES2CES1TSHRALOX15
SCHEMBL24704036 0.79 TSHR (0.56) HPGDCES2CES1TSHRALOX15
SCHEMBL2706993 0.79 CES2 (0.62) HPGDCES2CES1TSHRL3MBTL1
SCHEMBL19309855 0.76 ALDH1A1 (0.49) HPGDCES2CES1TSHRL3MBTL1
SCHEMBL191087 0.76 HPGD (0.48) HPGDCES2CES1TSHRL3MBTL1
SCHEMBL5917997 0.74 HPGD (0.47) HPGDCES2CES1TSHRL3MBTL1
SCHEMBL27672036 0.74 HPGD (0.47) HPGDCES2CES1TSHRL3MBTL1
SCHEMBL196916 0.74 CA1 (0.64) HPGDCES2CES1TSHRL3MBTL1
SCHEMBL5320832 0.74 TSHR (0.58) CES2CES1TSHRL3MBTL1ALOX15
SCHEMBL6025903 0.73 ERCC5 (0.65) HPGDL3MBTL1ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385213-B2 Candle wax compositions stabilized with UV absorbers and select hindered amine light stabilizers BASF SE (DE) 2019-08-20 US disclosed
US-20180002527-A1 CANDLE WAX COMPOSITIONS STABILIZED WITH UV ABSORBERS AND SELECT HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2018-01-04 US disclosed
WO-2016109789-A1 CANDLE WAX COMPOSITIONS STABILIZED WITH UV ABSORBERS AND SELECT HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2016-07-07 WO disclosed
US-20070256352-A1 Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith WOOD MERVIN G 2007-11-08 US disclosed
US-6905525-B2 Candle wax stabilized with piperazinones CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-06-14 US disclosed
EP-1252227-B1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SC HOLDING AG (CH) 2004-09-22 EP disclosed
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US disclosed
US-6547840-B2 White, dyed, dipped, unscented and/or scented candle wax is effectively stabilized against discoloration and fading by the incorporation of an imidazolidine in combination with a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-15 US disclosed
US-6544304-B2 White, dyed, dipped, unscented and/or scented candle wax stabilized against discoloration/fading by a morpholinone, e.g., 2,3,3,4,5,5-hexamethylmorpholin-2-one; including an ultra-violet absorber; oxidation resistance CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-08 US disclosed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US disclosed
US-20030005621-A1 Candle wax stabilized with morpholinones CIBA SPECIALTY CHEMICALS CORP. 2003-01-09 US disclosed
US-20030000128-A1 Candle wax stabilized with oxazolidines CIBA SPECIALTY CHEMICALS CORP. 2003-01-02 US disclosed
US-20030000130-A1 Candle wax stabilized with piperazinones CIBA SPECIALITY CHEMICALS CORP. 2003-01-02 US disclosed
US-20020194776-A1 Candle wax stabilized with imidazolidines CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
US-20020194777-A1 Candle wax stabilized with piperazinones CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1252227-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE Ciba SC Holding AG (CH) 2002-10-30 EP disclosed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
WO-2001057126-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed
US-6221115-B1 WHITE, DYED, DIPPED, UNSCENTED AND/OR SCENTED CANDLE WAX STABILIZED BY A ULTRAVILET RADIATION ABSORBER AND HINDERED AMINE STABILIZING AGENT CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070256352-A1 Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith CRY1, GPX4, CAND1 HPGD 847/4885CES2 930/4885CES1 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.