SCHEMBL5453986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5523767	0.86	CYP1A2 (0.58)	KIF11CYP1A2CYP3A4HDAC3HDAC4
	SCHEMBL13735692	0.84	HDAC3 (0.44)	CYP1A2CYP3A4HDAC3HDAC4HDAC1
	SCHEMBL30487756	0.82	MEN1 (0.59)	CYP1A2CYP3A4HDAC3HDAC4HDAC1
	SCHEMBL5690802	0.82	MEN1 (0.59)	CYP1A2CYP3A4HDAC3HDAC4HDAC1
	SCHEMBL35212106	0.81	CYP1A2 (0.55)	CYP1A2CYP3A4ALDH1A1CYP2C19NPSR1
	SCHEMBL14347168	0.81	CYP1A2 (0.55)	CYP1A2CYP3A4ALDH1A1CYP2C19NPSR1
	SCHEMBL5987435	0.78	LMNA (0.50)	KIF11CYP1A2CYP3A4HDAC3HDAC4
	SCHEMBL16143017	0.78	L3MBTL1 (0.52)	CYP1A2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL6555705	0.77	L3MBTL1 (0.46)	CYP1A2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL16096107	0.77	TGM2 (0.58)	CYP1A2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.