Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487756 | 1.00 | MEN1 (0.59) | MEN1KMT2AHSD17B10TDP1LMNA | |
| SCHEMBL22864579 | 0.87 | LMNA (0.58) | MEN1KMT2AHSD17B10TDP1LMNA | |
| SCHEMBL13735692 | 0.86 | HDAC3 (0.44) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL12781878 | 0.85 | MEN1 (0.70) | MEN1KMT2AHSD17B10TDP1LMNA | |
| SCHEMBL849875 | 0.85 | MEN1 (0.77) | MEN1KMT2AHSD17B10TDP1LMNA | |
| SCHEMBL5453986 | 0.82 | KIF11 (0.47) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL24197589 | 0.80 | LMNA (0.50) | MEN1KMT2AHSD17B10TDP1LMNA | |
| SCHEMBL16143017 | 0.79 | L3MBTL1 (0.52) | MEN1KMT2AALDH1A1MAPTHDAC3 | |
| SCHEMBL3928712 | 0.78 | LMNA (0.48) | MEN1KMT2AHSD17B10TDP1LMNA | |
| SCHEMBL1992521 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2AHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-24 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3849496-B1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | UNIV OREGON HEALTH & SCIENCE (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3849496-B1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | UNIV OREGON HEALTH & SCIENCE (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-112804982-B | Near infrared nerve-retaining benzo [ c ] phenoxazine fluorophores | 俄勒冈健康与科学大学 | 2023-07-25 | — | — | CN | disclosed |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-02-10 | — | — | US | disclosed |
| CN-112804982-A | Benzo [ c ] phenoxazine fluorophores for near-infrared nerve retention | 俄勒冈健康与科学大学 | 2021-05-14 | — | — | CN | disclosed |
| WO-2020056046-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-03-19 | — | — | WO | disclosed |
| WO-2018106646-A1 | AMINOTRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-06-14 | — | — | WO | disclosed |
| WO-2018106646-A1 | AMINOTRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-06-14 | — | — | WO | disclosed |
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | MEN1 1747/4885KMT2A 2752/4885HSD17B10 1828/4885 |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | NTRK1, PMP22, PAX3 | MEN1 1747/4885KMT2A 2752/4885HSD17B10 1828/4885 |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | MEN1 1747/4885KMT2A 2752/4885HSD17B10 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.