Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176260 | 0.78 | GABRA1 (0.42) | ALDH1A1 | |
| SCHEMBL10626556 | 0.76 | TSHR (0.36) | ALDH1A1TSHR | |
| SCHEMBL7190874 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL1515066 | 0.76 | — | — | |
| SCHEMBL5604556 | 0.76 | CYP3A4 (0.35) | ALDH1A1CYP3A4ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL366548 | 0.76 | XDH (0.38) | ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL10457106 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL2362110 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL4025062 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL15936494 | 0.74 | ALOX5 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189663-B2 | Organic semiconductor device having an active dielectric layer comprising silsesquioxanes | LUCENT TECHNOLOGIES INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-20050148129-A1 | Organic semiconductor device having an active dielectric layer comprising silsesquioxanes | LUCENT TECHNOLOGIES INC. | 2005-07-07 | — | — | US | disclosed |
| US-5962113-A | POLYSILOXANE-AMIDE | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-10-05 | — | — | US | disclosed |
| US-5883219-A | COMPRISING SUBSTRATE, METALLIC CIRCUIT LINES POSITIONED ON SUBSTRATE, AND POROUS DIELECTRIC MATERIAL POSITIONED ON THE CIRCUIT LINES; THE DIELECTRIC MATERIAL COMPRISES THE REACTION PRODUCT OF AN ORGANIC POLYSILICA AND POLYAMIC ESTER | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-03-16 | — | — | US | disclosed |