Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176260 | 0.78 | GABRA1 (0.42) | ALDH1A1 | |
| SCHEMBL2362110 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL5604556 | 0.76 | CYP3A4 (0.35) | ALDH1A1CYP3A4ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL366548 | 0.76 | XDH (0.38) | ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL1515066 | 0.76 | — | — | |
| SCHEMBL5454290 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL4025062 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL11405121 | 0.76 | RAB9A (0.31) | — | |
| SCHEMBL11258836 | 0.76 | XDH (0.32) | ALDH1A1CYP3A4 | |
| SCHEMBL9854766 | 0.73 | GABRA1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576628-B1 | Matrix metalloprotease inhibitors; arthritis, corneal ulcers, arteriosclerosis | ROCHE DIAGNOSTICS GMBH (DE) | 2003-06-10 | — | — | US | claimed |