Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365348 | 0.90 | GAA (0.70) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL24416458 | 0.89 | ALDH1A1 (0.68) | ALDH1A1HPGDALOX12HTTGAA | |
| SCHEMBL6833853 | 0.86 | GAA (0.62) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL22957976 | 0.85 | GAA (0.71) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL24064909 | 0.85 | GAA (0.71) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL13754414 | 0.84 | GAA (0.65) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL5455317 | 0.82 | HSD17B10 (0.64) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL10267756 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1HPGDALOX12HTTCYP3A4 | |
| SCHEMBL11283059 | 0.81 | STAT3 (0.61) | ALDH1A1HPGDALOX12HTTTAS2R38 | |
| SCHEMBL7748287 | 0.81 | GAA (0.61) | ALDH1A1HPGDALOX12HTTTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339122-B2 | hTRPV1 chemical agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210171454-A1 | hTRPV1 CHEMICAL AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-06-10 | — | — | US | disclosed |
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180215705-A1 | hTRPV1 CHEMICAL AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-08-02 | — | — | US | disclosed |
| US-20180215705-A1 | hTRPV1 CHEMICAL AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-08-02 | — | — | US | disclosed |
| CN-106103348-B | The purposes of sulphur compound and selenium compound as the precursor of nano structural material | 哥伦比亚大学（纽约）理事会 | 2018-07-31 | — | — | CN | disclosed |
| CN-106103348-A | Sulphur compound and selenium compound are as the purposes of the precursor of nano structural material | 哥伦比亚大学（纽约）理事会 | 2016-11-09 | — | — | CN | disclosed |
| US-20160237345-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-08-18 | — | — | US | disclosed |
| EP-3049370-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | The Trustees of Columbia University in the City of New York (US) | 2016-08-03 | — | — | EP | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | SCLY, TST, SOD1 | ALDH1A1 1898/4885HPGD 1265/4885ALOX12 2405/4885 |
| US-20180215705-A1 | hTRPV1 CHEMICAL AGENTS | TRPV1, TRPA1, TRPV4 | ALDH1A1 1826/4885HPGD 644/4885ALOX12 694/4885 |
| US-20210171454-A1 | hTRPV1 CHEMICAL AGENTS | TRPV1, TRPA1, TRPV4 | ALDH1A1 1806/4885HPGD 632/4885ALOX12 590/4885 |
| US-11339122-B2 | hTRPV1 chemical agents | TRPV1, TRPA1, TRPV4 | ALDH1A1 1826/4885HPGD 644/4885ALOX12 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.