Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13735831 | 0.90 | SMN1; SMN2 (0.47) | LMNAMAPTHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL28366619 | 0.83 | CA1 (0.52) | TSHRKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL15445138 | 0.83 | TDP1 (0.52) | CES1CES2KMT2ALMNAMAPT | |
| SCHEMBL1702960 | 0.81 | MEN1 (0.44) | CES1CES2KMT2ALMNAMAPT | |
| SCHEMBL14638933 | 0.81 | CA1 (0.53) | CES1CES2KMT2ALMNAMAPT | |
| SCHEMBL926435 | 0.81 | HPGD (0.44) | TSHRCES1CES2KMT2ALMNA | |
| SCHEMBL28366477 | 0.81 | ALDH1A1 (0.42) | KMT2ACYP3A4LMNAHPGDSMN1; SMN2 | |
| SCHEMBL27154482 | 0.81 | RAB9A (0.44) | TSHRCES1CES2KMT2ALMNA | |
| SCHEMBL14638953 | 0.81 | TPMT (0.41) | MAPTKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL15999776 | 0.81 | HDAC8 (0.49) | KMT2ASMN1; SMN2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375771-A | Preparation method of chiral iron complex | 浙江九洲药业股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-114067923-A | Screening method for Lewis acid catalyzed diazo compound activation mode | 郑州轻工业大学 | 2022-02-18 | — | — | CN | claimed |
| CN-113372258-A | Indeno [1,2-b ] indole derivative and preparation method and application thereof | 常州大学 | 2021-09-10 | — | — | CN | claimed |
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | claimed |
| CN-110734441-B | 3, 3' -pyrrolidine indole spiro-compound and preparation method and application thereof | 广州大学 | 2020-09-04 | — | — | CN | claimed |
| CN-110734441-A | 3, 3' -pyrrolidine indole spiro-compound and preparation method and application thereof | 广州大学 | 2020-01-31 | — | — | CN | claimed |
| CN-103193662-A | Method for preparing Beta-amino ester through copper-catalyzed three-component coupling reaction | UNIV BEIJING SCIENCE & TECH | 2013-07-10 | — | — | CN | claimed |
| CN-101423488-B | Method for preparing dihydro pyrrole derivates | UNIV EAST CHINA NORMAL | 2010-06-23 | — | — | CN | claimed |
| CN-101423488-A | Method for preparing dihydro pyrrole derivates | UNIV EAST CHINA NORMAL (CN) | 2009-05-06 | — | — | CN | claimed |
| CN-101417970-A | Dihydropyrrole derivates and method for preparing intermediate pyrrolidine | UNIV EAST CHINA NORMAL (CN) | 2009-04-29 | — | — | CN | claimed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | claimed |
| US-6025502-A | CATALYTICALLY REACTING AN ARYL HYDRAZONE SUBSTITUTED ACETATE ESTER WITH A NITROGEN HETEROCYCLIC COMPOUND WHICH HAS THE NITROGEN PROTECTED, THEN DEPROTECTING | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-02-15 | — | — | US | claimed |
| CN-115873047-B | Chiral ferrocene P, N, N-ligand with side arm, synthesis method and application thereof | 中国科学院大连化学物理研究所 | 2025-06-10 | — | — | CN | disclosed |
| CN-116082237-B | Nitrogen-containing heterocyclic compound and preparation method thereof | 安徽中医药大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-116510786-B | Binuclear gold catalyst and preparation method and application thereof | 中山大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116496176-B | Preparation method of polysubstituted spiro cyclopropane derivative | 哈尔滨工业大学（深圳） | 2024-11-15 | — | — | CN | disclosed |
| EP-1173278-A1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064583-A1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-11-02 | — | — | WO | disclosed |
| US-6025502-A | CATALYTICALLY REACTING AN ARYL HYDRAZONE SUBSTITUTED ACETATE ESTER WITH A NITROGEN HETEROCYCLIC COMPOUND WHICH HAS THE NITROGEN PROTECTED, THEN DEPROTECTING | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | PPOX, PPIF, HMBS | TSHR 4034/4885SRC 2301/4885CES1 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.