Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | MB | P02144 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753834 | 0.89 | ALDH1A1 (0.50) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL11718858 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL5459330 | 0.84 | ALDH1A1 (0.62) | L3MBTL1GAAALDH1A1KMT2AMAPT | |
| SCHEMBL29654057 | 0.84 | ALDH1A1 (0.62) | L3MBTL1GAAALDH1A1KMT2AMAPT | |
| Acetaminophen SCHEMBL9696436 | 0.83 | ALDH1A1 (0.80) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL861674 | 0.83 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL2306600 | 0.83 | L3MBTL1 (0.57) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL1880013 | 0.83 | RAB9A (0.57) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL725810 | 0.83 | ALDH1A1 (0.75) | SMN1; SMN2L3MBTL1GAAALDH1A1KMT2A | |
| SCHEMBL11925383 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545480-A | Dithiazole derivatives as inhibitors of lysyl oxidase | 南卡罗来纳大学 | 2024-02-09 | — | — | CN | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| US-20220378753-A1 | NOVEL INHIBITORS OF LYSYL OXIDASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2022-12-01 | — | — | US | disclosed |
| CN-113004219-A | Thiazole ring-containing amide compound and preparation method and application thereof | 贵州大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378753-A1 | NOVEL INHIBITORS OF LYSYL OXIDASES | LOXL1, LOXL2, LOXL4 | SMN1; SMN2 1679/4885HTT 2952/4885L3MBTL1 12/4885 |
| US-11712437-B2 | Inhibitors of lysyl oxidases | LOXL1, LOXL2, LOXL4 | SMN1; SMN2 1726/4885HTT 2758/4885L3MBTL1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.