SCHEMBL5459265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5466077	0.86	RAB9A (0.52)	RAB9APOLBSMN1; SMN2DGAT1L3MBTL1
	SCHEMBL5465623	0.84	RAB9A (0.60)	RAB9APOLBSMN1; SMN2AURKAKDR
	SCHEMBL5452148	0.81	WNT3A (0.52)	RAB9APOLBSMN1; SMN2DGAT1MAPT
	SCHEMBL5460908	0.78	RAB9A (0.55)	RAB9APOLBSMN1; SMN2FLT3L3MBTL1
	SCHEMBL5459843	0.73	RAB9A (0.55)	RAB9ASMN1; SMN2L3MBTL1MAPTKDM4E
	SCHEMBL5451242	0.73	NPC1 (0.53)	RAB9APOLBSMN1; SMN2DGAT1MAPT
	SCHEMBL7490372	0.72	MAPT (0.59)	RAB9AL3MBTL1MAPTKDM4ECYP1A2
	SCHEMBL5452137	0.72	MEN1 (0.55)	RAB9APOLBSMN1; SMN2MAPTKDM4E
	SCHEMBL5466937	0.72	KMT2A (0.60)	RAB9APOLBSMN1; SMN2MAPTKDM4E
	SCHEMBL5466996	0.72	DGAT1 (0.55)	RAB9ASMN1; SMN2DGAT1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.