Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 15/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465886 | 1.00 | CPB2 (0.38) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL7261246 | 0.82 | CPB2 (0.40) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL3615288 | 0.82 | LTA4H (0.39) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL3615291 | 0.82 | LTA4H (0.39) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL29855050 | 0.71 | GRN (0.48) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL17771955 | 0.71 | GRN (0.48) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL5946004 | 0.70 | GRN (0.46) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL5946011 | 0.70 | GRN (0.46) | CPB2GRNSORT1CTSKCTSS | |
| SCHEMBL7260298 | 0.70 | CTSK (0.35) | CPB2CTSKCTSSCTSLCTSB | |
| SCHEMBL30063688 | 0.68 | GRN (0.46) | CPB2GRNSORT1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105892-A1 | Amidino compounds as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| EP-1697355-A2 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063742-A2 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105892-A1 | Amidino compounds as cysteine protease inhibitors | CTSF, CTSB, CTSS | CPB2 33/4885GRN 1041/4885SORT1 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.