Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956969 | 1.00 | MAOB (0.62) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL13229036 | 0.89 | MAOA (0.51) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL13229093 | 0.85 | MAOB (0.51) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL13229147 | 0.85 | MAOB (0.51) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL29268823 | 0.85 | KMT2A (0.51) | MAOBMAOAMEN1KMT2ARAB9A | |
| Naphthalene SCHEMBL29268753 | 0.84 | MAOB (0.57) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL12986699 | 0.84 | MAOB (0.57) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL12854020 | 0.84 | MAOB (0.71) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL61411 | 0.84 | MAOB (0.71) | MAOBMAOAMEN1KMT2ARAB9A | |
| SCHEMBL31061270 | 0.82 | HPGD (0.67) | MEN1KMT2ARAB9ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251034-A | Organic light emitting diode and organic light emitting device | 乐金显示有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-114751882-B | Synthesis method of benzofuran | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-217418619-U | Gas treatment pipeline system | 沧州中铁装备制造材料有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114751882-A | Synthetic method of benzofuran | 南京工业大学 | 2022-07-15 | — | — | CN | disclosed |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2021-06-15 | — | — | US | disclosed |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2021-06-15 | — | — | US | disclosed |
| US-10662206-B2 | Method for preparing silane derivatives from furan derivatives in presence of borane catalyst | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-05-26 | — | — | US | disclosed |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2020-04-23 | — | — | US | disclosed |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2020-04-23 | — | — | US | disclosed |
| US-20190263840-A1 | METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-08-29 | — | — | US | disclosed |
| CN-1543456-A | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | 惠氏公司 | 2004-11-03 | — | — | CN | disclosed |
| CN-1543456-A | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | 惠氏公司 | 2004-11-03 | — | — | CN | disclosed |
| EP-1401822-A1 | NAPHTHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | Wyeth (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6599925-B2 | Cardiovascular disorders; anticancer agents | WYETH | 2003-07-29 | — | — | US | disclosed |
| US-6599925-B2 | Cardiovascular disorders; anticancer agents | WYETH | 2003-07-29 | — | — | US | disclosed |
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH | 2003-01-23 | — | — | US | disclosed |
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH | 2003-01-23 | — | — | US | disclosed |
| WO-2003000671-A1 | NAPHTHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2003-01-03 | — | — | WO | disclosed |
| US-4133953-A | Process for the preparation of sulfonated benzofuran derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-09 | — | — | US | disclosed |
| US-3928390-A | Certain 2-substituted phenyl and substituted naphthyl benzofurans | HOECHST AG | 1975-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | F2R, SERPINE1, SERPINC1 | MAOB 1411/4885MAOA 1300/4885MEN1 4849/4885 |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | PAICS, AOC1, FLI1 | MAOB 351/4885MAOA 268/4885MEN1 56/4885 |
| US-10662206-B2 | Method for preparing silane derivatives from furan derivatives in presence of borane catalyst | PFAS, HPD, FDPS | MAOB 1328/4885MAOA 891/4885MEN1 1121/4885 |
| US-20190263840-A1 | METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST | PFAS, HPD, FDPS | MAOB 1328/4885MAOA 891/4885MEN1 1121/4885 |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | PAICS, AOC1, FLI1 | MAOB 351/4885MAOA 268/4885MEN1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.