Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553255 | 0.90 | KMT2A (0.54) | MEN1KMT2ASIGMAR1KDM4E | |
| SCHEMBL5395547 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2ASIGMAR1MCHR1KDM4E | |
| SCHEMBL10967640 | 0.87 | LMNA (0.55) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL13962943 | 0.86 | MEN1 (0.46) | MEN1KMT2ASIGMAR1MCHR1KDM4E | |
| SCHEMBL13962921 | 0.83 | MEN1 (0.46) | MEN1KMT2ASIGMAR1KDM4EHTT | |
| SCHEMBL7292577 | 0.82 | OPRM1 (0.57) | SIGMAR1SLC6A12TMEM97MCHR1KDM4E | |
| SCHEMBL13962938 | 0.82 | MEN1 (0.56) | MEN1KMT2AKDM4E | |
| SCHEMBL13962874 | 0.80 | SIGMAR1 (0.54) | MEN1KMT2ASIGMAR1KDM4EHTT | |
| SCHEMBL13962841 | 0.79 | CHRM2 (0.51) | MEN1KMT2ASIGMAR1KDM4EHTT | |
| SCHEMBL10967944 | 0.75 | HTT (0.54) | MEN1KMT2ASIGMAR1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110684-B2 | Diaza-spiro [4.5] decanes useful as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100227862-A1 | DIAZA-SPIRO [4.5] DECANES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| EP-1979354-A1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | Syngeta Participations AG (CH) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085945-A1 | DIAZA-SPIRO [4 . 5] DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227862-A1 | DIAZA-SPIRO [4.5] DECANES USEFUL AS PESTICIDES | DDT, CHRM1, DECR1 | MEN1 2349/4885KMT2A 1619/4885SIGMAR1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.