SCHEMBL547144

SCHEMBL547144

NC(CS)C(=O)NC(Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.58
USP2 O75604 1/20 0.58
EGFR P00533 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
ALOX15 P16050 1/20 0.58
PTGS1 P23219 1/20 0.58
HTR2A P28223 1/20 0.58
PTGS2 P35354 1/20 0.58
RECQL P46063 1/20 0.58
SLC7A5 Q01650 1/20 0.58
HIF1A Q16665 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
MME P08473 7/20 0.50
ACE P12821 1/20 0.50
YARS1 P54577 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232700 1.00 KDM4E (0.58) KDM4EUSP2EGFRLCKFYN
SCHEMBL9432921 1.00 KDM4E (0.58) KDM4EUSP2EGFRLCKFYN
SCHEMBL27830772 1.00 KDM4E (0.58) KDM4EUSP2EGFRLCKFYN
SCHEMBL11792982 0.91 SLC7A5 (0.68) KDM4EUSP2EGFRLCKFYN
Hydrochloric Acid SCHEMBL11454672 0.89 SLC7A5 (0.66) KDM4EUSP2EGFRLCKFYN
SCHEMBL13925361 0.87 LCK (0.58) KDM4EUSP2EGFRLCKFYN
SCHEMBL25471928 0.86 YARS1 (0.68) KDM4EUSP2EGFRLCKFYN
SCHEMBL25405730 0.86 YARS1 (0.68) KDM4EUSP2EGFRLCKFYN
SCHEMBL23085897 0.86 YARS1 (0.68) KDM4EUSP2EGFRLCKFYN
SCHEMBL11854054 0.86 SLC7A5 (0.61) KDM4EUSP2EGFRLCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576166-B2 Contrast agents for detection of enzyme activities based on melanin synthesis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-17 US claimed
US-20230248849-A1 CONTRAST AGENTS FOR DETECTION OF ENZYME ACTIVITIES BASED ON MELANIN SYNTHESIS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-08-10 US claimed
WO-2022026381-A1 CONTRAST AGENTS FOR DETECTION OF ENZYME ACTIVITIES BASED ON MELANIN SYNTHESIS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-02-03 WO claimed
US-20190292405-A1 SLURRIES FOR CHEMICAL MECHANICAL POLISHING OF COBALT CONTAINING SUBSTRATES FUJIMI INCORPORATED (JP) 2019-09-26 US claimed
EP-1478389-A1 TREATMENT FOR DISEASES OF THE EYE, INNER EAR AND CENTRAL NERVOUS SYSTEM CEVEC Pharmaceuticals GmbH (DE) 2004-11-24 EP claimed
WO-2003070269-A1 TREATMENT FOR DISEASES OF THE EYE, INNER EAR AND CENTRAL NERVOUS SYSTEM CEVEC PHARMACEUTICALS GMBH (DE) 2003-08-28 WO claimed
EP-0664114-B1 Process and kit for dyeing hair with catechols and a persulfate oxidizing agent CLAIROL INC (US) 2003-04-02 EP claimed
US-20260096975-A1 ACTIVE INGREDIENT COMBINATIONS OF ALKYLAMIDOTHIAZOLES AND ONE OR MORE BIOPOLYMERS BEIERSDORF AG (DE) 2026-04-09 US disclosed
US-12584905-B2 Method for identifying molecular markers of children's skin LABORATOIRES EXPANSCIENCE (FR) 2026-03-24 US disclosed
US-12576166-B2 Contrast agents for detection of enzyme activities based on melanin synthesis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-17 US disclosed
US-20260070944-A1 PEPTIDE PROMOTING TYROSINASE ACTIVITY AND USE THEREOF HYSENSBIO CO., LTD (KR) 2026-03-12 US disclosed
US-20260062555-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING NORTHWESTERN UNIVERSITY (US) 2026-03-05 US disclosed
US-12441890-B2 Selenium-containing analogues of pheomelanin and related materials and methods of making NORTHWESTERN UNIVERSITY (US) 2025-10-14 US disclosed
US-5240715-A Exposure to oxidizing or reducing agent ADVANCED POLYMER SYSTEMS (US) 1993-08-31 US disclosed
EP-0547065-A1 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS Biosource Technologies, Inc. (US) 1993-06-23 EP disclosed
EP-0574383-A4 COLOR MODIFIED MELANINS AND METHODS FOR THEIR PREPARATION AND USE. ADVANCED POLYMER SYSTEMS INC (US) 1993-03-19 EP disclosed
US-5188844-A Oxidation and reduction to change dark color to light color compatible with human skin; useful ingrediants in sunscreen cosmetic formulations ADVANCED POLYMER SYSTEMS, INC. (US) 1993-02-23 US disclosed
US-5120325-A Color-matched sterile adhesive bandages containing melanin-like pigment composition FLESHTONES PRODUCTS CO., INC. (US) 1992-06-09 US disclosed
WO-1992000373-A1 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS BIOSOURCE GENETICS CORPORATION (CA) 1992-01-09 WO disclosed
WO-1991017738-A1 COLOR MODIFIED MELANINS AND METHODS FOR THEIR PREPARATION AND USE ADVANCED POLYMER SYSTEMS, INC. (US) 1991-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584905-B2 Method for identifying molecular markers of children's skin KRT18, SERPINA6, COLGALT1 KDM4E 4351/4885USP2 2843/4885EGFR 4168/4885
US-12576166-B2 Contrast agents for detection of enzyme activities based on melanin synthesis TYR, MPO, LNPEP KDM4E 2741/4885USP2 199/4885EGFR 1704/4885
US-20260096975-A1 ACTIVE INGREDIENT COMBINATIONS OF ALKYLAMIDOTHIAZOLES AND ONE OR MORE BIOPOLYMERS TYR, GALE, GALK1 KDM4E 3921/4885USP2 3841/4885EGFR 3203/4885
US-20230248849-A1 CONTRAST AGENTS FOR DETECTION OF ENZYME ACTIVITIES BASED ON MELANIN SYNTHESIS TYR, MPO, RNASE1 KDM4E 3951/4885USP2 378/4885EGFR 2822/4885
US-12441890-B2 Selenium-containing analogues of pheomelanin and related materials and methods of making SELENOI, SCLY, SELP KDM4E 3403/4885USP2 3122/4885EGFR 2971/4885
US-20260070944-A1 PEPTIDE PROMOTING TYROSINASE ACTIVITY AND USE THEREOF TYR, ARGLU1, ARG1 KDM4E 1367/4885USP2 2721/4885EGFR 1011/4885
US-20260062555-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING TYR, MPO, SCLY KDM4E 4475/4885USP2 3706/4885EGFR 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.