Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472389 | 1.00 | CCKBR (0.39) | CCKBRCCKARNTRK1DAPK3PRKD3 | |
| SCHEMBL5822163 | 0.77 | NTRK1 (0.48) | CCKBRCCKARNTRK1DAPK3PRKD3 | |
| SCHEMBL5468659 | 0.76 | NTRK1 (0.47) | CCKBRCCKARNTRK1DAPK3PRKD3 | |
| SCHEMBL5469781 | 0.72 | PBRM1 (0.51) | CCKBRCCKARNTRK1DAPK3PRKD3 | |
| SCHEMBL5822242 | 0.69 | ALDH1A1 (0.53) | CCKBRCCKARLRRK2MEN1RAB9A | |
| SCHEMBL5813081 | 0.68 | NTRK1 (0.48) | CCKBRCCKARNTRK1DAPK3PRKD3 | |
| SCHEMBL5822194 | 0.66 | KMT2A (0.46) | CCKBRCCKARMEN1KMT2ALMNA | |
| SCHEMBL8688581 | 0.62 | GABRP (0.50) | GPR84HAT1EP300MEN1KMT2A | |
| SCHEMBL30681308 | 0.62 | IDO1 (0.57) | PDGFRALTKLRRK2MEN1RAB9A | |
| SCHEMBL7304930 | 0.62 | IDO1 (0.57) | PDGFRALTKLRRK2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167488-A1 | Novel therapeutic use | LEO PHARMA A/S (DK) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167488-A1 | Novel therapeutic use | MAG, PMP22, MYT1 | CCKBR 1771/4885CCKAR 2707/4885NTRK1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.