Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 13/20 | 0.57 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462058 | 0.87 | HTR2A (0.49) | HTR7HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL5461887 | 0.84 | HTR7 (0.40) | HTR7HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL5468004 | 0.83 | HTR7 (0.51) | HTR7HTR6KDM4EALDH1A1TDP1 | |
| SCHEMBL5473526 | 0.83 | HTR1A (0.43) | HTR7HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL5468106 | 0.82 | DRD2 (0.42) | HTR7HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL5263240 | 0.81 | DRD2 (0.62) | HTR7HTR2AHTR2CHTR1ADRD4 | |
| SCHEMBL5336144 | 0.78 | HTR7 (0.55) | HTR7HTR6KDM4EALDH1A1TDP1 | |
| SCHEMBL5468144 | 0.77 | ALDH1A1 (0.53) | HTR7KDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL5481420 | 0.77 | HTR7 (0.47) | HTR7HTR6HTR2AHTR1ADRD4 | |
| SCHEMBL5502062 | 0.74 | DRD2 (0.62) | HTR7KDM4EALDH1A1TDP1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | claimed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | HTR7 19/4885HTR6 9/4885KDM4E 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.