Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475249 | 0.84 | KDM4E (0.53) | ALDH1A1ALOX15KDM4ECYP3A4HPGD | |
| SCHEMBL2747082 | 0.81 | KDM4E (0.47) | ALDH1A1ALOX15KDM4ECA12CA1 | |
| SCHEMBL11119681 | 0.80 | METAP2 (0.38) | ALDH1A1KDM4EHPGDMAPTPOLB | |
| SCHEMBL9467542 | 0.79 | KDM1A (0.36) | — | |
| SCHEMBL11233815 | 0.78 | METAP2 (0.39) | ALDH1A1KDM4EHPGDMAPTPOLB | |
| SCHEMBL30293277 | 0.77 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4ECYP3A4TDP1 | |
| SCHEMBL3103198 | 0.76 | KDM4E (0.43) | ALDH1A1ALOX15KDM4ECYP3A4HPGD | |
| SCHEMBL3123352 | 0.76 | KDM4E (0.43) | ALDH1A1ALOX15KDM4ECYP3A4HPGD | |
| SCHEMBL3049402 | 0.76 | ALOX5AP (0.37) | ALDH1A1ALOX15KDM4ECYP3A4TDP1 | |
| SCHEMBL6853710 | 0.75 | KDM4E (0.42) | ALDH1A1ALOX15KDM4ECYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023340-B2 | Wnt inhibitors for human stem cell differentiation | CHEMREGEN, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20130177535-A1 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION | CHEMREGEN, INC | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130177535-A1 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION | WNT3A, WNT1, WNT3 | ALDH1A1 767/4885ALOX15 4464/4885KDM4E 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.