Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471348 | 0.86 | TAS1R3 (0.30) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27682238 | 0.78 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL5473120 | 0.77 | TRPV1 (0.46) | — | |
| SCHEMBL5233556 | 0.76 | KDM4C (0.39) | — | |
| SCHEMBL5175753 | 0.76 | PTGDR2 (0.35) | — | |
| SCHEMBL5930810 | 0.74 | GSK3B (0.30) | — | |
| SCHEMBL5467037 | 0.73 | MTNR1A (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5174956 | 0.71 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5930665 | 0.71 | PTGDR2 (0.34) | — | |
| SCHEMBL5471655 | 0.71 | NR3C1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | SCHERING AG (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | TNF, CXCL8, MPO | HSD11B1 441/4885TAS1R3 2020/4885TAS1R1 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.