SCHEMBL5477265

SCHEMBL5477265

COC(=O)N(Cl)c1cc[c]cc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28401782 0.80 L3MBTL1 (0.46) MAPTHPGDALDH1A1ALOX15NPSR1
SCHEMBL2535672 0.78 PGR (0.41) ALDH1A1ALOX15NPSR1L3MBTL1
SCHEMBL7197824 0.78
SCHEMBL5472838 0.77 ROCK2 (0.30)
SCHEMBL5476076 0.77 ALDH1A1 (0.31) MAPTHPGDALDH1A1ALOX15NPSR1
SCHEMBL11774597 0.77 MEN1 (0.44) MAPTHPGDALDH1A1NPSR1L3MBTL1
SCHEMBL5472705 0.74
SCHEMBL10099722 0.74 L3MBTL1 (0.38) MAPTHPGDALDH1A1ALOX15NPSR1
SCHEMBL2534649 0.74 HTT (0.48) MAPTHPGDALDH1A1
SCHEMBL27500355 0.73 OPRM1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD MAPT 3974/4885HPGD 976/4885ALDH1A1 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.