Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.84 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.84 |
| ▸ | POLB | P06746 | 3/20 | 0.84 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.84 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.84 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.84 |
| ▸ | USP7 | Q93009 | 2/20 | 0.84 |
| ▸ | RECQL | P46063 | 2/20 | 0.84 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.84 |
| ▸ | CTSD | P07339 | 1/20 | 0.84 |
| ▸ | PTPRF | P10586 | 1/20 | 0.84 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.84 |
| ▸ | CETP | P11597 | 1/20 | 0.84 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.84 |
| ▸ | CES1 | P23141 | 1/20 | 0.84 |
| ▸ | ACP1 | P24666 | 1/20 | 0.84 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547774 | 1.00 | PTPN1 (0.84) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL14132123 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL13395361 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL18428537 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL12300180 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL23314191 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL16994210 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL19714770 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL21819718 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL5713287 | 0.91 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245744-A1 | INTRANASAL ADMINSTRATION OF CANNABIGEROL, CBDa, CBGa, & UNCARIA TOMENTOSA HYDROALCOHOLIC EXTRACT COMPOUNDS EMULSIFIED IN SALINE HOMOGENOUS SOLUTION FOR INTRANASAL ADMINISTRATION | CLARK ARTIS ASAHEL (US) | 2024-07-25 | — | — | US | claimed |
| CN-107115568-A | Self assembly lysozyme multilayer membrane preparation method with antibiotic property and biocompatibility | 温州生物材料与工程研究所 | 2017-09-01 | — | — | CN | claimed |
| CN-106798947-A | A kind of self-assembled protein multilayer membrane preparation method | 温州生物材料与工程研究所 | 2017-06-06 | — | — | CN | claimed |
| US-20100227827-A1 | METHOD OF INCREASING TRYPTOPHAN AND NICOTINAMIDE LEVELS IN VIVO | GENETIC HEALTH ENTERPRISES (PTY) LTD. (ZA) | 2010-09-09 | — | — | US | claimed |
| US-20080206162-A1 | Composition and Methods for Treating Alzheimer's Disease and Other Amyloidoses | UNIVERSITY OF WASHINGTON | 2008-08-28 | — | — | US | claimed |
| WO-2008008837-A2 | A METHOD OF INCREASING TRYPTOPHAN AND NICOTINAMIDE LEVELS IN VIVO | LYNPETE TRADING 6 (PTY) LTD. TRADING AS GENETIC HEALTH ENTERPRISES (ZA) | 2008-01-17 | — | — | WO | claimed |
| EP-1019044-B1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2007-04-11 | — | — | EP | claimed |
| US-20040086585-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-06 | — | — | US | claimed |
| US-20040076698-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-22 | — | — | US | claimed |
| EP-1019044-A4 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2004-01-07 | — | — | EP | claimed |
| US-20010055630-A1 | Compostion and methods for treating alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-12-27 | — | — | US | claimed |
| EP-1019044-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | University of Washington (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1998051302-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIVERSITY OF WASHINGTON (US) | 1998-11-19 | — | — | WO | claimed |
| US-4606911-A | PENTACYCLIC ACID TRITERPENES | ROHTO PHARMACEUTICAL CO. LTD. (JP) | 1986-08-19 | — | — | US | claimed |
| US-20240100113-A1 | TERPENE-CONTAINING COMPOSITIONS | QSI HOLDING COMPANY INC (US) | 2024-03-28 | — | — | US | disclosed |
| WO-2022124583-A1 | COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASES, COMPRISING QUINOVIC ACID | 경상국립대학교 산학협력단 | 2022-06-16 | — | — | WO | disclosed |
| US-20210346453-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF COVID-19 | COGNITIVE CLARITY INC. (US) | 2021-11-11 | — | — | US | disclosed |
| US-5648449-A | Copolyesters, molded articles from the same and aromatic triols used for producing the same | KURARAY CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0725051-A2 | Copolyesters, molded articles from the same and aromatic triols used for producing the same | KURARAY CO., LTD. (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-4606911-A | PENTACYCLIC ACID TRITERPENES | ROHTO PHARMACEUTICAL CO. LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227827-A1 | METHOD OF INCREASING TRYPTOPHAN AND NICOTINAMIDE LEVELS IN VIVO | NNMT, AADAT, AANAT | PTPN1 4034/4885SENP1 2330/4885POLB 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.