Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471442 | 0.82 | HPGD (0.42) | ALOX5MME | |
| SCHEMBL162736 | 0.78 | SRC (0.50) | ALOX5PTGS1LCKFYNDAO | |
| Hydrochloric Acid SCHEMBL11244144 | 0.76 | SRC (0.48) | ALOX5PTGS1LCKFYNDAO | |
| SCHEMBL10918696 | 0.76 | SRC (0.48) | ALOX5PTGS1LCKFYNDAO | |
| SCHEMBL5466726 | 0.75 | SRC (0.37) | SRCPTGS2 | |
| SCHEMBL9814548 | 0.73 | ALOX5 (0.50) | ALOX5PTGS1LCKFYNDAO | |
| SCHEMBL5462469 | 0.73 | ALOX5 (0.44) | ALOX5PTGS1DAOPTGS2CES2 | |
| SCHEMBL200194 | 0.73 | LMNA (0.52) | ALOX5LCKFYNDAOCHRNB2 | |
| SCHEMBL9329422 | 0.73 | LMNA (0.52) | ALOX5LCKFYNDAOCHRNB2 | |
| SCHEMBL9814555 | 0.72 | ALOX5 (0.41) | ALOX5PTGS1LCKFYNDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149605-A1 | Substituted pyrrole derivatives as hmg-coa reductase inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2007-06-28 | — | — | US | disclosed |
| EP-1643988-A1 | SUBSTITUTED PYRROLE DERIVATIVES AS HMG-COA REDUCTASE INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004105752-A1 | SUBSTITUTED PYRROLE DERIVATIVES AS HMG-COA REDUCTASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149605-A1 | Substituted pyrrole derivatives as hmg-coa reductase inhibitors | HMGCR, CYP46A1, GRHPR | ALOX5 452/4885PTGS1 119/4885LCK 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.