SCHEMBL7909976

SCHEMBL7909976

Cc1cccc(-c2c3cc4ccccc4cc3c(-c3cccc(C)c3)c3cc4ccccc4cc23)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
RAB9A P51151 3/20 0.44
ACHE P22303 1/20 0.44
CNR1 P21554 2/20 0.44
CNR2 P34972 2/20 0.44
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
NPC1 O15118 2/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HEXA P06865 1/20 0.42
HEXB P07686 1/20 0.42
ENPP1 P22413 1/20 0.42
NR1I3 Q14994 2/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27930163 0.86 ALOX5 (0.52) CYP2A6RAB9AACHECNR1CNR2
SCHEMBL488939 0.85 ACHE (0.50) RAB9AACHECNR1CNR2NPC1
SCHEMBL20809931 0.81 CNR1 (0.49) RAB9AACHECNR1CNR2NPC1
SCHEMBL7487894 0.81 ACHE (0.46) RAB9AACHECNR1CNR2NPC1
SCHEMBL29446786 0.79 KMT2A (0.56) RAB9AESR1ESR2NPC1HPGD
SCHEMBL602106 0.79 KMT2A (0.56) RAB9AESR1ESR2NPC1HPGD
SCHEMBL28172800 0.79 ENPP3 (0.43) CYP2A6TDP1RAB9AACHECNR1
SCHEMBL7906815 0.78 ESR1 (0.50) ESR1ESR2KMT2A
SCHEMBL18858085 0.78 L3MBTL1 (0.57) TDP1RAB9ANPC1HPGDTSHR
SCHEMBL12115266 0.78 ITGA4 (0.38) RAB9ACNR1CNR2NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6203933-B1 ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND TDK CORPORATION (JP) 2001-03-20 US disclosed