SCHEMBL548032

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL547716	0.94	FABP4 (0.41)	FABP4FABP3LMNAALDH1A1RAB9A
	SCHEMBL27284024	0.82	ALDH1A1 (0.42)	FABP4FABP3LMNAALDH1A1RAB9A
	SCHEMBL547149	0.81	FOLH1 (0.42)	FABP4FABP3LMNAALDH1A1RAB9A
	SCHEMBL548482	0.81	LMNA (0.48)	LMNAALDH1A1RAB9AMAPTHTT
	SCHEMBL547148	0.75	HNF4A (0.50)	FABP4FABP3LMNAALDH1A1RAB9A
	SCHEMBL12679971	0.74	LMNA (0.50)	LMNAALDH1A1RAB9AMAPTHTT
	SCHEMBL2846662	0.74	LMNA (0.52)	FABP4FABP3LMNAALDH1A1RAB9A
	SCHEMBL3446771	0.74	LMNA (0.52)	FABP4FABP3LMNAALDH1A1RAB9A
	SCHEMBL548557	0.73	LMNA (0.36)	LMNAALDH1A1MAPTFOLH1
	SCHEMBL1635941	0.72	LMNA (0.50)	FABP4FABP3LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.