Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486856 | 0.85 | ALDH1A1 (0.69) | POLBKCNA5HTR1AALDH1A1SMN1; SMN2 | |
| SCHEMBL5482274 | 0.85 | L3MBTL1 (0.62) | KCNA5HTR1AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3985948 | 0.80 | HRH3 (0.67) | ALDH1A1SMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL15349833 | 0.80 | KDM4E (0.70) | KCNA5HTR1AALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL5481509 | 0.79 | DRD2 (0.67) | KCNA5HTR1AALDH1A1DRD2HTR2A | |
| SCHEMBL2177120 | 0.79 | HRH2 (0.49) | POLBALDH1A1HRH2HRH1 | |
| SCHEMBL5487159 | 0.77 | TSHR (0.55) | POLBKCNA5ALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL5480294 | 0.77 | HPGD (0.61) | POLBKCNA5ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5487964 | 0.76 | DRD2 (0.51) | KCNA5ALDH1A1SMN1; SMN2DRD2KMT2A | |
| SCHEMBL20512386 | 0.76 | POLB (0.48) | POLBKCNA5HTR1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |