Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598812 | 0.87 | CYSLTR2 (0.50) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL12261507 | 0.86 | ALDH1A1 (0.55) | CYP1A2CYP2C19MAPTHTR2BKMT2A | |
| SCHEMBL24893443 | 0.81 | L3MBTL1 (0.65) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| 1-Ethoxy-2-Pentoxybenzene SCHEMBL1276813 | 0.80 | L3MBTL1 (0.69) | CYP1A2CYP2C9CYP2C19LMNAMEN1 | |
| SCHEMBL11605622 | 0.79 | PPARG (0.60) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL9214705 | 0.79 | LMNA (0.61) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL462017 | 0.79 | SIGMAR1 (0.50) | CYSLTR2CYSLTR1LMNAMEN1NR1I2 | |
| Water SCHEMBL15923699 | 0.78 | PPARG (0.50) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL7636542 | 0.78 | L3MBTL1 (0.67) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL28515930 | 0.78 | L3MBTL1 (0.67) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032555-A1 | Novel aryloxyphenyl-propanamines | CONCERT PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | US | disclosed |
| EP-0399504-A2 | Aryloxyphenylpropylamines their preparation and use | NOVO NORDISK A/S (DK) | 1990-11-28 | — | — | EP | disclosed |
| EP-0318727-A2 | Aryloxphenylpropylamines and their preparation and use | NOVO NORDISK A/S (DK) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032555-A1 | Novel aryloxyphenyl-propanamines | SLC6A2, SLC6A3, SLC18A1 | CYP1A2 200/4885CYP2C9 725/4885CYP2C19 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.