Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480355 | 0.86 | LMNA (0.48) | LMNAMCOLN3MAPK1HSD11B1KMT2A | |
| SCHEMBL11509430 | 0.78 | LMNA (0.72) | ALDH1A1LMNAMCOLN3HPGDMAPK1 | |
| SCHEMBL12626953 | 0.72 | KMT2A (0.63) | PARLALDH1A1LMNAHSD11B1SMN1; SMN2 | |
| SCHEMBL5475968 | 0.70 | POLB (0.50) | ALDH1A1LMNAHPGDMAPK1KMT2A | |
| SCHEMBL30858424 | 0.69 | DDB1 (0.64) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1519692 | 0.69 | ALDH1A1 (0.69) | PARLALDH1A1LMNAHSD11B1SMN1; SMN2 | |
| Ethylene SCHEMBL8377931 | 0.69 | KMT2A (0.59) | PARLALDH1A1LMNAHSD11B1SMN1; SMN2 | |
| SCHEMBL5482658 | 0.69 | KDM4E (0.47) | ALDH1A1LMNAHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL20379965 | 0.69 | KMT2A (0.76) | ALDH1A1LMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL16150923 | 0.68 | HSD11B1 (0.55) | ALDH1A1LMNAMCOLN3HPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | MAPK1, NOS1, NOS2 | PARL 4023/4885ALDH1A1 1694/4885CTSG 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.