Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487435 | 0.84 | CTSL (0.40) | MAPK1RAB9AATM | |
| SCHEMBL4188373 | 0.82 | CTSS (0.39) | MAPK1RAB9AATM | |
| SCHEMBL4171002 | 0.81 | CTSL (0.49) | — | |
| SCHEMBL4183292 | 0.81 | USP30 (0.39) | SMN1; SMN2RAB9AATMALDH1A1 | |
| SCHEMBL4175687 | 0.80 | CNR1 (0.44) | MAPK1RAB9AATMALDH1A1 | |
| SCHEMBL5484030 | 0.80 | MAPK1 (0.38) | MAPK1RAB9AATM | |
| SCHEMBL5484032 | 0.80 | RAB9A (0.41) | SMN1; SMN2RAB9ALMNAATMALDH1A1 | |
| SCHEMBL4181987 | 0.80 | CTSL (0.43) | RAB9AATMALDH1A1 | |
| SCHEMBL4186154 | 0.79 | CTSS (0.42) | ATMALDH1A1 | |
| SCHEMBL4179274 | 0.79 | CNR1 (0.43) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869026-A1 | NOVEL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105475-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |