Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185692 | 0.93 | CTSL (0.45) | RAB9ACTSSCTSLCTSKCTSB | |
| SCHEMBL4188282 | 0.89 | CTSS (0.54) | CTSSCTSLCTSKCTSBATM | |
| SCHEMBL4178441 | 0.88 | CTSL (0.47) | RAB9ACTSSCTSLCTSKCTSB | |
| SCHEMBL4181130 | 0.86 | CTSS (0.48) | CTSSCTSLCTSKCTSBALDH1A1 | |
| SCHEMBL4191791 | 0.86 | CTSB (0.42) | CTSSCTSLCTSKCTSBATM | |
| SCHEMBL4185689 | 0.85 | ATM (0.42) | RAB9ACTSSCTSLCTSKCTSB | |
| SCHEMBL5485436 | 0.81 | ATM (0.38) | RAB9AALDH1A1ATMRENCNR1 | |
| SCHEMBL5484026 | 0.80 | MAPK1 (0.47) | RAB9AALDH1A1ATMLMNASMN1; SMN2 | |
| SCHEMBL4171001 | 0.78 | ATM (0.41) | RAB9AALDH1A1ATMKDM4EBCHE | |
| SCHEMBL4190119 | 0.78 | ATM (0.40) | RAB9AALDH1A1ATMRENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869026-A1 | NOVEL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-12-26 | — | — | EP | claimed |
| WO-2006105475-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-05 | — | — | WO | claimed |
| US-20070135307-A1 | Inhibition of tuber sprouting | ACETO AGRICULTURAL CHEMICALS CORP. (US) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135307-A1 | Inhibition of tuber sprouting | PF4, PDGFA, PDGFRB | RAB9A 3239/4885CTSS 3397/4885CTSL 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.