Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484713 | 0.90 | DRD2 (0.47) | SIGMAR1DRD2CACNA1GPYGLDRD4 | |
| SCHEMBL5479482 | 0.84 | MEN1 (0.49) | SIGMAR1DRD2MAPK1DRD4DRD3 | |
| SCHEMBL5482967 | 0.82 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1DRD2CACNA1GMAPT | |
| SCHEMBL5483920 | 0.81 | MEN1 (0.42) | SIGMAR1ALDH1A1DRD2CACNA1GDRD4 | |
| SCHEMBL2178789 | 0.80 | FAAH (0.41) | SIGMAR1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL2177270 | 0.72 | FAAH (0.41) | ALDH1A1DRD2MAPTHPGDTSHR | |
| SCHEMBL23705502 | 0.70 | CRBN (0.50) | ALDH1A1TSHR | |
| SCHEMBL5480984 | 0.70 | HRH3 (0.46) | SIGMAR1MAPK1SLC6A4HRH3 | |
| SCHEMBL2932153 | 0.69 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1KDM4ESMN1; SMN2CACNA1G | |
| SCHEMBL7009189 | 0.68 | PYGL (0.48) | ALDH1A1KDM4EPYGLMAPTPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |