Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482967 | 0.92 | SIGMAR1 (0.45) | MEN1KMT2ACACNA1GSIGMAR1DRD2 | |
| SCHEMBL5479482 | 0.82 | MEN1 (0.49) | MEN1KMT2ASIGMAR1DRD2DRD4 | |
| SCHEMBL5484273 | 0.81 | SIGMAR1 (0.48) | CACNA1GSIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL4306833 | 0.80 | FAAH (0.46) | MEN1KMT2ACACNA1GALDH1A1 | |
| SCHEMBL5484713 | 0.80 | DRD2 (0.47) | MEN1KMT2ACACNA1GSIGMAR1DRD2 | |
| SCHEMBL5480294 | 0.75 | HPGD (0.61) | MEN1KMT2AALDH1A1THRBKCNA5 | |
| SCHEMBL4309408 | 0.73 | FAAH (0.45) | MEN1KMT2ACACNA1GALDH1A1 | |
| SCHEMBL3606690 | 0.73 | UBE2M (0.47) | KMT2ASIGMAR1DRD4ALDH1A1 | |
| SCHEMBL5487159 | 0.72 | TSHR (0.55) | MEN1KMT2ADRD2ALDH1A1THRB | |
| SCHEMBL27655162 | 0.72 | LMNA (0.43) | MEN1KMT2ADRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |