Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483920 | 0.92 | MEN1 (0.42) | SIGMAR1MEN1KMT2ACACNA1GDRD2 | |
| SCHEMBL5484273 | 0.82 | SIGMAR1 (0.48) | SIGMAR1CACNA1GDRD2DRD4DRD3 | |
| SCHEMBL3606690 | 0.81 | UBE2M (0.47) | SIGMAR1KMT2ADRD4LMNAALDH1A1 | |
| SCHEMBL5479482 | 0.81 | MEN1 (0.49) | SIGMAR1MEN1KMT2ADRD2DRD4 | |
| SCHEMBL4309408 | 0.81 | FAAH (0.45) | MEN1KMT2ACACNA1GTSHRLMNA | |
| SCHEMBL5484713 | 0.79 | DRD2 (0.47) | SIGMAR1MEN1KMT2ACACNA1GDRD2 | |
| SCHEMBL2982101 | 0.75 | DCUN1D1 (0.42) | CACNA1G | |
| SCHEMBL5480294 | 0.74 | HPGD (0.61) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL5487159 | 0.74 | TSHR (0.55) | MEN1KMT2ADRD2TSHRALDH1A1 | |
| SCHEMBL27655162 | 0.74 | LMNA (0.43) | MEN1KMT2ADRD2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |