SCHEMBL5486063

SCHEMBL5486063

CC(C)C(=O)OCOc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
MTNR1A P48039 4/20 0.49
MTNR1B P49286 4/20 0.49
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
ELANE P08246 1/20 0.46
RAB9A P51151 2/20 0.43
PKM P14618 1/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
THRB P10828 1/20 0.42
PTPRC P08575 1/20 0.42
PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113298 0.83 THRB (0.57) LMNAMTNR1AMTNR1BTDP1RAB9A
SCHEMBL1871138 0.83 THRB (0.57) LMNAMTNR1AMTNR1BTDP1RAB9A
SCHEMBL14296162 0.81 RXRA (0.50) RAB9ANPC1KDM4ESMN1; SMN2L3MBTL1
SCHEMBL10075124 0.81 MTNR1A (0.53) LMNAMTNR1AMTNR1BALOX15TDP1
SCHEMBL13279930 0.80 THRB (0.54) LMNAMTNR1AMTNR1BTDP1RAB9A
SCHEMBL10075120 0.80 MAPT (0.50) LMNAMTNR1AMTNR1BALOX15TDP1
SCHEMBL17928316 0.80 ELANE (0.50) LMNAMTNR1AMTNR1BTDP1ELANE
SCHEMBL896992 0.80 ALDH1A1 (0.53) LMNAMTNR1AMTNR1BALOX15TDP1
SCHEMBL29140273 0.79 ALOX15 (0.56) MTNR1AMTNR1BALOX15TDP1RAB9A
SCHEMBL4965677 0.79 ALOX15 (0.56) MTNR1AMTNR1BALOX15TDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070066506-A1 Sulfosuccinates COGNIS IP MANAGEMENT GMBH (DE) 2007-03-22 US disclosed