Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302103 | 0.78 | TUBB1 (0.33) | FFAR1FFAR4TUBB1PAX8PTGS2 | |
| SCHEMBL12880355 | 0.77 | ALOX5 (0.43) | FFAR1FFAR4CD274PTGS2 | |
| SCHEMBL548087 | 0.75 | CD274 (0.46) | CD274TUBB1PTGS2 | |
| SCHEMBL13664220 | 0.74 | TUBB1 (0.33) | FFAR1FFAR4TUBB1PAX8PTGS2 | |
| SCHEMBL14963927 | 0.73 | RAPGEF4 (0.33) | CD274 | |
| SCHEMBL12865413 | 0.72 | FFAR1 (0.33) | FFAR1FFAR4 | |
| SCHEMBL2608090 | 0.68 | PTGS2 (0.38) | CD274PAX8PTGS2 | |
| SCHEMBL4306354 | 0.67 | PDE1A (0.36) | FFAR1FFAR4 | |
| SCHEMBL4311273 | 0.67 | FFAR1 (0.31) | FFAR1FFAR4 | |
| SCHEMBL17359287 | 0.66 | VRK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263798-B2 | Optically active quaternary ammonium salt having axial asymmetry, and method for producing alpha-amino acid and derivative thereof by using the same | NAGASE & CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8252952-B2 | Optically active quaternary ammonium salt having axial asymmetry, and method for producing alpha-amino acid and derivative thereof by using the same | NAGASE & CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20120108846-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120101310-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120101309-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120095218-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120095252-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-8110680-B2 | Optically active quaternary ammonium salt having axial asymmetry, and method for producing alpha-amino acid and derivative thereof by using the same | NAGASE & CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20100029935-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108846-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | FFAR1 2613/4885FFAR4 2871/4885CD274 4570/4885 |
| US-20120101309-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | FFAR1 3412/4885FFAR4 3217/4885CD274 4572/4885 |
| US-20120095252-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | FFAR1 2613/4885FFAR4 2871/4885CD274 4570/4885 |
| US-20120095218-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | FFAR1 2613/4885FFAR4 2871/4885CD274 4570/4885 |
| US-20120101310-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | FFAR1 2613/4885FFAR4 2871/4885CD274 4570/4885 |
| US-20100029935-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | FFAR1 2613/4885FFAR4 2871/4885CD274 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.