Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272776 | 0.83 | GFER (0.50) | TDP1CA2CAMK2AALDH1A1CNR2 | |
| Succinic Acid SCHEMBL27434396 | 0.82 | LMNA (0.53) | TDP1L3MBTL1GABRR1GAAALDH1A1 | |
| Succinic Acid SCHEMBL6544596 | 0.82 | LMNA (0.53) | TDP1L3MBTL1GABRR1GAAALDH1A1 | |
| SCHEMBL2028391 | 0.82 | CA2 (0.65) | TDP1L3MBTL1CA2CAMK2AGAA | |
| SCHEMBL10275399 | 0.82 | CNR2 (0.45) | TDP1CA2CAMK2AGAAALDH1A1 | |
| SCHEMBL2131696 | 0.81 | AKR1B1 (0.62) | TDP1L3MBTL1GAAALDH1A1CYP2C19 | |
| SCHEMBL39103 | 0.81 | CA2 (0.62) | TDP1CA2CAMK2AGAAALDH1A1 | |
| SCHEMBL1331730 | 0.81 | CA2 (0.62) | TDP1CA2CAMK2AGAAALDH1A1 | |
| SCHEMBL2397311 | 0.80 | L3MBTL1 (0.66) | TDP1L3MBTL1CA2CAMK2AALDH1A1 | |
| SCHEMBL11388782 | 0.80 | CTBP2 (0.50) | TDP1L3MBTL1ALDH1A1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | MAPK1, NOS1, NOS2 | TDP1 1340/4885L3MBTL1 3449/4885CA2 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.