Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598227 | 0.74 | PIN1 (0.40) | ADORA2AALDH1A1 | |
| SCHEMBL27991818 | 0.71 | ADORA2A (0.55) | ADORA2AMAPK1MAPTHTTNPSR1 | |
| SCHEMBL6415423 | 0.71 | DHFR (0.49) | — | |
| SCHEMBL30288591 | 0.71 | NPC1 (0.49) | MAPK1MAPTDRD2DRD4DRD3 | |
| SCHEMBL2579619 | 0.70 | ALKBH1 (0.43) | LMNA | |
| SCHEMBL5473956 | 0.69 | ADORA2A (0.51) | ADORA2AMAPK1MAPTHTTNPSR1 | |
| SCHEMBL14574878 | 0.69 | ATP4A (0.43) | ADORA2AMAPK1MAPTHTTNPSR1 | |
| SCHEMBL11865948 | 0.69 | L3MBTL1 (0.42) | ADORA2AMAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL28328153 | 0.68 | NOTUM (0.52) | ADORA2AMAPK1MAPTHTTNPSR1 | |
| SCHEMBL29448371 | 0.68 | HSP90AB1 (0.59) | MAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | ITO MASHITO | 2007-07-19 | — | — | US | disclosed |
| CN-1942188-A | Pyrimidine derivatives and their use as agricultural and horticultural fungicides | BAYER CROPSCIENCE AG (DE) | 2007-04-04 | — | — | CN | disclosed |
| EP-1718305-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | Bayer CropScience AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005079798-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | DPYD, DHFR, TYMP | ADORA2A 311/4885MAPK1 3295/4885MAPT 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.