SCHEMBL5487096

SCHEMBL5487096

O=C(O)c1ccccc1-c1ccc(-c2ccccc2)cc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 4/20 0.61
HNF4A P41235 3/20 0.61
MCL1 Q07820 2/20 0.61
DHFR P00374 1/20 0.61
FOLH1 Q04609 2/20 0.57
PTPN1 P18031 2/20 0.53
ATM Q13315 2/20 0.52
CDC25B P30305 1/20 0.52
GSTA1 P08263 1/20 0.51
DCLRE1A Q6PJP8 1/20 0.50
DCLRE1B Q9H816 1/20 0.50
IKBKB O14920 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX12 P18054 1/20 0.49
MEN1 O00255 1/20 0.48
APAF1 O14727 1/20 0.48
NPC1 O15118 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21879680 0.94 ACMSD (0.68) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL593979 0.88 ACMSD (0.66) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL31517115 0.88 ACMSD (0.59) ACMSDHNF4AMCL1DHFRFOLH1
Biphenyl SCHEMBL6250985 0.88 HNF4A (0.63) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL32677769 0.84 HNF4A (0.64) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL505412 0.84 HNF4A (0.64) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL32677772 0.84 HNF4A (0.64) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL2892457 0.82 ACMSD (0.59) ACMSDHNF4AMCL1DHFRFOLH1
SCHEMBL7252300 0.82 ACMSD (0.59) ACMSDHNF4AMCL1DHFRPTPN1
SCHEMBL9847733 0.82 FOLH1 (0.51) ACMSDHNF4AMCL1DHFRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114025956-A Laminated body 日东电工株式会社 2022-02-08 CN disclosed
EP-1679346-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-11-14 EP disclosed
US-20070123617-A1 Polyacetal resin composition DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2007-05-31 US disclosed
EP-1679346-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-12 EP disclosed
EP-0349844-A2 Thermotropic wholly aromatic polyesters having a low processing temperature, process for their preparation and their use in the preparation of shaped articles, filaments, fibres and films BAYER AG (DE) 1990-01-10 EP disclosed