Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.66 |
| ▸ | HNF4A | P41235 | 2/20 | 0.66 |
| ▸ | DHFR | P00374 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.53 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.50 |
| ▸ | EIF4E | P06730 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892457 | 0.94 | ACMSD (0.59) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL21879680 | 0.94 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL5487096 | 0.88 | ACMSD (0.61) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL31517115 | 0.87 | ACMSD (0.59) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL28694686 | 0.84 | DCLRE1B (0.56) | ACMSDHNF4ADHFRMCL1DCLRE1B | |
| SCHEMBL31413664 | 0.84 | SMN1; SMN2 (0.53) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL5951431 | 0.84 | SMN1; SMN2 (0.53) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL2462821 | 0.83 | ACMSD (0.66) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL32677772 | 0.83 | HNF4A (0.64) | ACMSDHNF4ADHFRMCL1PTPN1 | |
| SCHEMBL505412 | 0.83 | HNF4A (0.64) | ACMSDHNF4ADHFRMCL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110862368-B | Photocatalytic oxidation synthesis method of benzocoumarin compound | 浙江工业大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-110862368-A | Photocatalytic oxidation synthesis method of benzocoumarin compound | 浙江工业大学 | 2020-03-06 | — | — | CN | disclosed |
| US-8114993-B2 | Use of aryl chlorides in palladium-catalyzed C-H bond functionalization | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2012-02-14 | — | — | US | disclosed |
| US-8114993-B2 | Use of aryl chlorides in palladium-catalyzed C-H bond functionalization | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2012-02-14 | — | — | US | disclosed |
| US-8114993-B2 | Use of aryl chlorides in palladium-catalyzed C-H bond functionalization | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2012-02-14 | — | — | US | disclosed |
| US-20090012293-A1 | USE OF ARYL CHLORIDES IN PALLADIUM-CATALYZED C-H BOND FUNCTIONALIZATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-01-08 | — | — | US | disclosed |
| US-20090012293-A1 | USE OF ARYL CHLORIDES IN PALLADIUM-CATALYZED C-H BOND FUNCTIONALIZATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-01-08 | — | — | US | disclosed |
| US-20090012293-A1 | USE OF ARYL CHLORIDES IN PALLADIUM-CATALYZED C-H BOND FUNCTIONALIZATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-01-08 | — | — | US | disclosed |
| EP-0507576-A1 | Polypropylene-based resin compositions | TOSOH CORPORATION (JP) | 1992-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012293-A1 | USE OF ARYL CHLORIDES IN PALLADIUM-CATALYZED C-H BOND FUNCTIONALIZATION | DBH, DDT, CYCS | ACMSD 3149/4885HNF4A 957/4885DHFR 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.