Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12815920 | 0.87 | CALM1 (0.46) | CALM1HTR2ABCL2BCL2L1HPGD | |
| SCHEMBL12816441 | 0.78 | HTR2A (0.41) | CALM1HTR2ABCL2BCL2L1HPGD | |
| SCHEMBL972711 | 0.75 | CALM1 (0.69) | CALM1HTR2ABCL2BCL2L1HPGD | |
| SCHEMBL12817614 | 0.75 | HTR2A (0.39) | CALM1HTR2ABCL2BCL2L1HPGD | |
| SCHEMBL937353 | 0.75 | ALDH1A1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL12815404 | 0.74 | CALM1 (0.46) | CALM1HTR2ABCL2BCL2L1HPGD | |
| SCHEMBL13924104 | 0.74 | HTR2A (0.41) | CALM1HTR2ABCL2BCL2L1HPGD | |
| SCHEMBL2524726 | 0.73 | IDO1 (0.50) | — | |
| SCHEMBL4841457 | 0.73 | PNMT (0.34) | — | |
| SCHEMBL10709160 | 0.73 | GABRA1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |