SCHEMBL5489433

SCHEMBL5489433

Cc1ccc(C)c(Cc2ncc[nH]2)c1C

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 11/20 0.72
HTR1A P08908 1/20 0.54
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
ALOX15 P16050 1/20 0.38
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36
TERT O14746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL952640 0.84 TAAR1 (0.64) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL953782 0.84 TAAR1 (1.00) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL28277587 0.83 TAAR1 (0.67) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL954645 0.81 TAAR1 (0.65) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL956439 0.78 TAAR1 (0.65) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL953405 0.77 TAAR1 (0.59) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL952973 0.77 TAAR1 (0.79) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL955414 0.76 TAAR1 (0.69) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL2776944 0.76 TAAR1 (0.68) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL955142 0.76 TAAR1 (0.82) TAAR1HTR1AADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157078-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-01-02 US claimed
US-20040170661-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2004-09-02 US claimed
US-6716421-B2 BAIT MATRICES AND BAIT STATIONS FOR ELIMINATING TERMITE COLONIES AND UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-04-06 US claimed
US-20030124164-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2003-07-03 US claimed
US-20030124166-A1 Termiticidal bait matrix can be used in a bait station installed in the ground. FLORIDA RESEARCH FOUNDATION, INC., THE UNIVERSITY OF 2003-07-03 US claimed
US-20030017187-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2003-01-23 US claimed
US-20020172658-A1 Devices and methods for eliminating termite colonies FLORIDA RESEARCH FOUNDATION, INC., THE UNIVERSITY OF 2002-11-21 US claimed
WO-2002069704-A2 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2002-09-12 WO claimed
US-7157078-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-01-02 US disclosed
US-6969512-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-11-29 US disclosed
US-6964124-B2 Devices and methods for eliminating termite colonies UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-11-15 US disclosed
US-20040170661-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2004-09-02 US disclosed
WO-2004032625-A2 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2004-04-22 WO disclosed
US-6716421-B2 BAIT MATRICES AND BAIT STATIONS FOR ELIMINATING TERMITE COLONIES AND UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-04-06 US disclosed
WO-2003105580-A1 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2003-12-24 WO disclosed
WO-2003106395-A1 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2003-12-24 WO disclosed
US-20030124164-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2003-07-03 US disclosed
US-20020172658-A1 Devices and methods for eliminating termite colonies FLORIDA RESEARCH FOUNDATION, INC., THE UNIVERSITY OF 2002-11-21 US disclosed
WO-2002069704-A2 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030124166-A1 Termiticidal bait matrix can be used in a bait station installed in the ground. CA3, ADAMTS12, MMP7 TAAR1 916/4885HTR1A 3392/4885ADRA2A 4843/4885
US-20040170661-A1 Devices and methods for eliminating termite colonies CA3, MLN, TRHDE TAAR1 1014/4885HTR1A 3940/4885ADRA2A 4781/4885
US-20030124164-A1 Devices and methods for eliminating termite colonies CA3, MLN, TRHDE TAAR1 1014/4885HTR1A 3940/4885ADRA2A 4781/4885
US-20020172658-A1 Devices and methods for eliminating termite colonies CA3, MLN, TRHDE TAAR1 1014/4885HTR1A 3940/4885ADRA2A 4781/4885
US-20030017187-A1 Devices and methods for eliminating termite colonies CA3, PHB1, COX6C TAAR1 352/4885HTR1A 2770/4885ADRA2A 4707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.