Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495153 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPK14SMOL3MBTL1MAPT | |
| SCHEMBL5489948 | 0.73 | MAPK14 (0.48) | ALDH1A1MAPK14SMOL3MBTL1MAPT | |
| SCHEMBL307472 | 0.63 | P2RX7 (0.50) | ALDH1A1L3MBTL1MAPTLMNAPOLB | |
| SCHEMBL6883040 | 0.62 | RAB9A (0.67) | ALDH1A1L3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL4164590 | 0.61 | HTT (0.54) | ALDH1A1L3MBTL1RAB9ALMNAMEN1 | |
| SCHEMBL5480980 | 0.61 | MAPK14 (0.46) | ALDH1A1MAPK14SMOL3MBTL1MAPT | |
| SCHEMBL38658667 | 0.60 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL30397636 | 0.60 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL12764365 | 0.60 | SMN1; SMN2 (0.58) | ALDH1A1MAPK14SMOL3MBTL1MAPT | |
| SCHEMBL1248162 | 0.60 | P2RX7 (0.66) | ALDH1A1L3MBTL1LMNAPOLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |