Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489948 | 0.85 | MAPK14 (0.48) | ALDH1A1MAPTRAB9AP2RX7MAPK14 | |
| SCHEMBL5488200 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTRAB9AP2RX7MAPK14 | |
| SCHEMBL6883040 | 0.68 | RAB9A (0.67) | ALDH1A1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL5480980 | 0.66 | MAPK14 (0.46) | ALDH1A1MAPTRAB9AMAPK14SMO | |
| SCHEMBL4541485 | 0.66 | MAPT (0.42) | ALDH1A1MAPTRAB9AMAPK14KMT2A | |
| SCHEMBL12764365 | 0.65 | SMN1; SMN2 (0.58) | ALDH1A1MAPTRAB9AMAPK14SMO | |
| SCHEMBL5495156 | 0.65 | MAPK14 (0.49) | ALDH1A1MAPTRAB9AMAPK14SMO | |
| SCHEMBL12764388 | 0.65 | SMN1; SMN2 (0.57) | ALDH1A1MAPTRAB9AMAPK14SMO | |
| SCHEMBL5489952 | 0.64 | MAPK14 (0.48) | ALDH1A1MAPTRAB9AMAPK14SMO | |
| SCHEMBL4164590 | 0.64 | HTT (0.54) | ALDH1A1RAB9AP2RX7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |