Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789999 | 0.87 | HTR3E (0.43) | ADRA2AADRA2BADRA2CNOS3NOS1 | |
| SCHEMBL7790448 | 0.87 | HTR3A (0.43) | ADRA2AADRA2BADRA2CNOS3NOS1 | |
| SCHEMBL1720891 | 0.86 | ALDH1A1 (0.41) | NOS3NOS1 | |
| SCHEMBL8697303 | 0.73 | GABRP (0.38) | ADRA2AADRA2BADRA2CNOS3 | |
| SCHEMBL7794049 | 0.71 | HTR3A (0.39) | ADRA2AADRA2BADRA2CNOS3NOS1 | |
| SCHEMBL10502034 | 0.71 | ALDH1A1 (0.38) | POLBNOS3NOS1 | |
| SCHEMBL8696375 | 0.70 | HTR3E (0.50) | POLBNOS3NOS1 | |
| SCHEMBL10775857 | 0.70 | HTR3E (0.50) | — | |
| SCHEMBL10503151 | 0.68 | MIF (0.35) | POLB | |
| SCHEMBL6651377 | 0.68 | PLG (0.40) | NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211119-B2 | Coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-05-01 | — | — | US | disclosed |
| US-20060000032-A1 | Novel coupling components | HENKEL AG & CO. KGAA (DE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060000032-A1 | Novel coupling components | KRT18, C9, H1-4 | ADRA2A 4083/4885ADRA2B 3912/4885ADRA2C 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.