Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 2/20 | 0.56 |
| ▸ | KLK1 | P06870 | 2/20 | 0.56 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150345 | 0.82 | DEGS1 (0.78) | DEGS1NR1H4NPC1RAB9AMEN1 | |
| SCHEMBL368228 | 0.82 | DEGS1 (0.78) | DEGS1NR1H4NPC1RAB9AMEN1 | |
| SCHEMBL11426057 | 0.82 | CYP3A4 (0.58) | DEGS1NR1H4NPC1RAB9AMEN1 | |
| SCHEMBL8438773 | 0.81 | PLG (0.74) | DEGS1PLGKLK1KLK6NPC1 | |
| SCHEMBL2534284 | 0.81 | NR4A1 (0.63) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7067826 | 0.81 | MEN1 (0.71) | NPC1RAB9AMEN1KMT2ACHRNB2 | |
| SCHEMBL5494830 | 0.78 | MCL1 (0.71) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2466597 | 0.77 | MEN1 (0.65) | DEGS1NR1H4PLGKLK1KLK6 | |
| SCHEMBL28323302 | 0.76 | KDM4E (0.50) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL845143 | 0.76 | TERT (0.80) | KLK1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328507-B1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | UNIV NEW YORK STATE RES FOUND (US) | 2007-03-14 | — | — | EP | disclosed |
| CN-1249019-C | Naphthylsalicylanilides as antimicrobial and antiinflammatory agents | NEW YORK STATE UNIVERSITY RES (US) | 2006-04-05 | — | — | CN | disclosed |
| CN-1249019-C | Naphthylsalicylanilides as antimicrobial and antiinflammatory agents | NEW YORK STATE UNIVERSITY RES (US) | 2006-04-05 | — | — | CN | disclosed |
| CN-1468210-A | Naphthylsalicylanilides as antimicrobial and antiinflammatory agents | ŦԼ������ѧ�о������ | 2004-01-14 | — | — | CN | disclosed |
| CN-1468210-A | Naphthylsalicylanilides as antimicrobial and antiinflammatory agents | ŦԼ������ѧ�о������ | 2004-01-14 | — | — | CN | disclosed |
| EP-1328507-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | The Research Foundation Of State University of New York (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-1328507-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | The Research Foundation Of State University of New York (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6407288-B1 | AS ANTIBACTERIAL AGAINST GRAM NEGATIVE AND GRAM POSITIVE BACTERIA AND AS ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-06-18 | — | — | US | disclosed |
| US-6407288-B1 | AS ANTIBACTERIAL AGAINST GRAM NEGATIVE AND GRAM POSITIVE BACTERIA AND AS ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-06-18 | — | — | US | disclosed |
| US-6407288-B1 | AS ANTIBACTERIAL AGAINST GRAM NEGATIVE AND GRAM POSITIVE BACTERIA AND AS ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-06-18 | — | — | US | disclosed |
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2002-05-30 | — | — | US | disclosed |
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2002-05-30 | — | — | US | disclosed |
| WO-2002028819-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2002028819-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | PTGES3, FPR3, PTGS1 | DEGS1 1410/4885NR1H4 747/4885PLG 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.