SCHEMBL752816

SCHEMBL752816

O=S(=O)(c1ccccc1)n1cccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
PKM P14618 2/20 0.52
FBP1 P09467 1/20 0.52
HTR6 P50406 3/20 0.48
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
CYP2C9 P11712 2/20 0.48
MMP2 P08253 1/20 0.48
PARL Q9H300 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28057150 0.88 CA1 (0.53) CA1CA2PKMFBP1HTR6
SCHEMBL28910701 0.80 CA1 (0.46) CA1CA2PKMFBP1ALDH1A1
SCHEMBL1364805 0.79 CA1 (1.00) CA1CA2PKMFBP1ALDH1A1
SCHEMBL16059915 0.79 CA1 (0.59) CA1CA2PKMFBP1HTR6
SCHEMBL3018059 0.79 CA2 (0.64) CA1CA2PKMFBP1KMT2A
Imidazole SCHEMBL21065544 0.79 CA1 (0.45) CA1CA2PKMFBP1HTR6
SCHEMBL12419386 0.79 CA2 (0.58) CA1CA2PKMFBP1TSHR
SCHEMBL20741109 0.77 CA1 (0.50) CA1CA2PKMFBP1HTR6
SCHEMBL28053766 0.76 PKM (0.57) CA1CA2PKMHTR6ALDH1A1
SCHEMBL22112764 0.75 PARL (0.48) CA1CA2PKMHTR6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12046717-B2 Nonaqueous electrolyte compositions comprising a fluorinated solvent and a 2-furanone SYENSQO SA (BE) 2024-07-23 US claimed
WO-2024098538-A1 METHOD FOR MANUFACTURING SOLAR CELL BY DOPING PEROVSKITE BULK WITH SULFONYL MOLECULES 中国科学院合肥物质科学研究院 2024-05-16 WO claimed
CN-114854160-B Conductive hydrogel based on water-soluble polypyrrole and preparation method thereof 山东大学 2023-03-10 CN claimed
CN-115633531-A Method for preparing solar cell by doping sulfonyl molecules in perovskite phase 中国科学院合肥物质科学研究院 2023-01-20 CN claimed
CN-114854160-A Conductive hydrogel based on water-soluble polypyrrole and preparation method thereof 山东大学 2022-08-05 CN claimed
CN-109942543-A A kind of synthetic method of moxifloxacin hydrochloride light degradation impurity 山东齐都药业有限公司 2019-06-28 CN claimed
CN-108383828-A 1 new, 2- as chemokine receptor modulators is bis--sulfamide derivative 阿勒根公司 2018-08-10 CN claimed
EP-2955173-B1 1,2-BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS ALLERGAN INC (US) 2017-10-04 EP claimed
US-9603834-B2 1,2- bis-sulfonamide derivatives as chemokine receptor modulators ALLERGAN, INC. (US) 2017-03-28 US claimed
US-20160228407-A1 NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS ALLERGAN, INC. 2016-08-11 US claimed
CN-1422270-A Salts of bicyclic N-acylated imidazol-3-amines and imidazol-5-amines GRUELENTHAL GMBH (DE) 2003-06-04 CN claimed
JP-2003511456-A 2003-03-25 JP claimed
EP-1274709-A1 SALTS OF BICYCLIC, N-ACYLATED IMIDAZO-3-AMINES AND IMIDAZO-5-AMINES Grünenthal GmbH (DE) 2003-01-15 EP claimed
US-20020183320-A1 Bicyclic imidazo-5-yl-amine derivatives GRUENENTHAL GMBH (DE) 2002-12-05 US claimed
EP-1218383-A2 BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES Grünenthal GmbH (DE) 2002-07-03 EP claimed
US-6336963-B1 INK COMPOSITION COMPRISING INK VEHICLE COMPRISING FIRST NITRILE COMPOUND HAVING FIRST VISCOSITY AT MELT TEMPERATURE, VISCOSITY MODIFIER COMPRISING SECOND NITRILE COMPOUND HAVING LOWER VISCOSITY AT MELT TEMPERATURE, COLORANT XEROX CORPORATION 2002-01-08 US claimed
WO-2001081344-A1 SALTS OF BICYCLIC, N-ACYLATED IMIDAZO-3-AMINES AND IMIDAZO-5-AMINES Grünenthal GmbH (DE) 2001-11-01 WO claimed
WO-2001027118-A2 BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES Grünenthal GmbH (DE) 2001-04-19 WO claimed
WO-2001027119-A2 SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES Grünenthal GmbH (DE) 2001-04-19 WO claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160228407-A1 NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS CXCR2, CCR2, CX3CR1 CA1 3491/4885CA2 1696/4885PKM 3507/4885
US-20020183320-A1 Bicyclic imidazo-5-yl-amine derivatives ACHE, P2RX5, CNR1 CA1 1298/4885CA2 901/4885PKM 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.