Sugi Predict

Sugi Predict / Compounds / SCHEMBL5492952

SCHEMBL5492952

SCHEMBL5492952

CCOC(=O)SCc1ccco1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.50
▸ HSD17B10 Q99714 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ POLB P06746 2/20 0.50
▸ USP2 O75604 1/20 0.50
▸ NPC1 O15118 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ TSHR P16473 3/20 0.44
▸ HPGD P15428 2/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ MAOB P27338 2/20 0.42
▸ MAOA P21397 1/20 0.42
▸ TRPM8 Q7Z2W7 1/20 0.42
▸ TP53 P04637 1/20 0.42
▸ LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875124 0.79 ALDH1A1 (0.45) ALDH1A1HSD17B10MAPTPOLBNPC1
SCHEMBL10528051 0.79 ALDH1A1 (0.62) ALDH1A1HSD17B10MAPTPOLBUSP2
Ethyl Acetate SCHEMBL29859561 0.79 ALDH1A1 (0.52) ALDH1A1HSD17B10MAPTPOLBUSP2
SCHEMBL1532547 0.78 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPTPOLBUSP2
SCHEMBL526409 0.78 ALDH1A1 (0.53) ALDH1A1HSD17B10MAPTPOLBNPC1
SCHEMBL25385095 0.77 ALDH1A1 (0.53) ALDH1A1HSD17B10MAPTPOLBUSP2
SCHEMBL1532451 0.76 ALDH1A1 (0.55) ALDH1A1HSD17B10MAPTPOLBUSP2
SCHEMBL5491879 0.75 TSHR (0.54) ALDH1A1HSD17B10MAPTPOLBUSP2
SCHEMBL11328058 0.75 TSHR (0.44) ALDH1A1HSD17B10MAPTPOLBUSP2
SCHEMBL1645027 0.75 ALDH1A1 (0.54) ALDH1A1HSD17B10MAPTPOLBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 — — EP claimed
EP-1170295-B1 Thiocarbonates as flavour precursors QUEST INT (NL) 2007-12-19 — — EP claimed
US-6852350-B2 Flavor precursors FITZ WOLFGANG (NL) 2005-02-08 — — US claimed
US-20020037349-A1 Flavour precursors FITZ WOLFGANG (NL) 2002-03-28 — — US claimed
EP-1170295-A1 Thiocarbonates as flavour precursors QUEST INTERNATIONAL NEDERLAND BV (NL) 2002-01-09 — — EP claimed
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 — — EP disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 — — US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 — — CN disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 — — US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 — — US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 — — US disclosed
EP-1170295-B1 Thiocarbonates as flavour precursors QUEST INT (NL) 2007-12-19 — — EP disclosed
EP-1170295-B1 Thiocarbonates as flavour precursors QUEST INT (NL) 2007-12-19 — — EP disclosed
US-6852350-B2 Flavor precursors FITZ WOLFGANG (NL) 2005-02-08 — — US disclosed
US-20020037349-A1 Flavour precursors FITZ WOLFGANG (NL) 2002-03-28 — — US disclosed
EP-1170295-A1 Thiocarbonates as flavour precursors QUEST INTERNATIONAL NEDERLAND BV (NL) 2002-01-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885HSD17B10 3230/4885MAPT 4340/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 ALDH1A1 1490/4885HSD17B10 4050/4885MAPT 930/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885HSD17B10 3230/4885MAPT 4340/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D ALDH1A1 1029/4885HSD17B10 1215/4885MAPT 286/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885HSD17B10 3230/4885MAPT 4340/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885HSD17B10 3230/4885MAPT 4340/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 ALDH1A1 3880/4885HSD17B10 3456/4885MAPT 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.