Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496259 | 0.94 | OPRM1 (0.52) | OPRM1OPRD1OPRK1SMN1; SMN2GAA | |
| SCHEMBL5492164 | 0.89 | TSHR (0.51) | OPRD1OPRK1GAAL3MBTL1KDM4E | |
| SCHEMBL4693977 | 0.82 | TSHR (0.57) | OPRD1OPRK1SMN1; SMN2GAAL3MBTL1 | |
| Carbamic Acid SCHEMBL4082824 | 0.79 | TSHR (0.53) | OPRD1OPRK1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL5494970 | 0.77 | MGLL (0.60) | GAACHRM2KDM4EHTTKMT2A | |
| SCHEMBL8490392 | 0.73 | CHRM1 (0.62) | SMN1; SMN2GAAALOX12L3MBTL1CHRM1 | |
| SCHEMBL13698470 | 0.72 | SMN1; SMN2 (0.74) | SMN1; SMN2GAAALOX12L3MBTL1CHRM1 | |
| SCHEMBL17363126 | 0.72 | CHRM2 (0.54) | SMN1; SMN2GAAALOX12L3MBTL1CHRM1 | |
| SCHEMBL9047536 | 0.71 | ALDH1A1 (0.58) | OPRM1OPRD1SMN1; SMN2GAACHRM1 | |
| SCHEMBL4917867 | 0.71 | OPRD1 (1.00) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066259-B1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-10 | — | — | EP | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |