Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693977 | 0.93 | TSHR (0.57) | TSHRLMNAOPRD1KDM4EGAA | |
| Carbamic Acid SCHEMBL4082824 | 0.89 | TSHR (0.53) | TSHRLMNAOPRD1KDM4EGAA | |
| SCHEMBL5493044 | 0.89 | OPRM1 (0.55) | TSHRLMNAOPRD1KDM4EGAA | |
| SCHEMBL5496259 | 0.83 | OPRM1 (0.52) | LMNAOPRD1KDM4EGAAOPRK1 | |
| SCHEMBL9047536 | 0.81 | ALDH1A1 (0.58) | LMNAOPRD1KDM4EGAAMAPT | |
| SCHEMBL9632474 | 0.78 | ALDH1A1 (0.49) | TSHRLMNAKDM4EGAAMAPT | |
| SCHEMBL10601711 | 0.77 | OPRM1 (0.60) | TSHRLMNAOPRD1GAAMAPT | |
| SCHEMBL5494970 | 0.76 | MGLL (0.60) | KDM4EGAATDP1KMT2A | |
| SCHEMBL14282904 | 0.76 | OPRD1 (0.50) | TSHROPRD1KDM4EOPRK1SETD7 | |
| SCHEMBL24621774 | 0.75 | KDM4E (0.53) | OPRD1KDM4ESETD7MAPK1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066259-B1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-10 | — | — | EP | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |
| EP-1066259-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051578-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-14 | — | — | WO | disclosed |