Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | CCR4 | P51679 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491436 | 0.99 | ADRB2 (0.72) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL27812589 | 0.94 | ADRB2 (0.67) | ADRB2ADRB1ADRB3RAB9AGAA | |
| Bromide SCHEMBL27812101 | 0.93 | ADRB2 (0.65) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL13181102 | 0.88 | ADRB2 (0.59) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL206453 | 0.83 | ADRB3 (0.59) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL13503715 | 0.82 | RAB9A (0.62) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL28007919 | 0.80 | ADRB2 (0.55) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL28818145 | 0.80 | ALDH1A1 (0.59) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL9385942 | 0.79 | CSNK2A1 (0.58) | ADRB2ADRB1ADRB3RAB9AGAA | |
| SCHEMBL28007948 | 0.79 | MAPT (0.62) | ADRB2ADRB1ADRB3GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262204-B2 | Modulation of CCR4 function | AMGEN INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7144903-B2 | CCR4 antagonists | AMGEN INC. (US) | 2006-12-05 | — | — | US | disclosed |
| EP-1578341-A4 | MODULATION OF CCR4 FUNCTION | TULARIK INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1578341-A2 | MODULATION OF CCR4 FUNCTION | Tularik Inc. (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040039035-A1 | Modulation of CCR4 function | TULARIK INC. | 2004-02-26 | — | — | US | disclosed |
| US-20030018022-A1 | Ccr4 antagonists | TULARIK INC. | 2003-01-23 | — | — | US | disclosed |
| WO-2002094264-A1 | CCR4 ANTAGONISTS | TULARIK INC. (US) | 2002-11-28 | — | — | WO | disclosed |
| US-20020173524-A1 | Modulation of CCR4 function | TULARIK INC. (US) | 2002-11-21 | — | — | US | disclosed |
| WO-2002030358-A2 | MODULATION OF CCR4 FUNCTION | TULARIK INC. (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018022-A1 | Ccr4 antagonists | CCR4, CCR1, CCR3 | ADRB2 476/4885ADRB1 322/4885ADRB3 285/4885 |
| US-20020173524-A1 | Modulation of CCR4 function | CCR4, CCR1, CCR3 | ADRB2 1170/4885ADRB1 734/4885ADRB3 542/4885 |
| US-20040039035-A1 | Modulation of CCR4 function | CCR4, CCR1, CCR3 | ADRB2 1170/4885ADRB1 734/4885ADRB3 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.